3-[(3-sec-butyl-4-hydroxybenzoyl)amino]azepan-4-yl 4-(2-hydroxy-5-methoxybenzoyl)benzoate

This compound is a synthetic small molecule belonging to the benzophenone class. It is known as a balanol analog and has been studied primarily as an experimental inhibitor of protein kinases. Specifically, it acts as an ATP-site competitive inhibitor of cAMP-dependent protein kinase (protein kinase A), and may also inhibit other related kinases such as serum/glucocorticoid regulated kinase family member SGK3. Its structure is based on modifications of balanol, a natural product known for potent inhibition of serine/threonine kinases[1][6][7][10]. The compound has not been approved for clinical use and remains experimental.

Other names

Balanol analog 8(3R,4R)-3-{3-[(2S)-butan-2-yl]-4-hydroxybenzamido}azepan-4-yl 4-(2-hydroxy-5-methoxybenzoyl)benzoate(3R,4R)-3-{3-[2S)-butan–2–yl]-4–hydroxybenzoyl}amino–azepanyl 4-(2-hydroxy–5-methoxybenzoyl)benzoate